Siric > Research > Clinical and Biological Databases – BCB

Biological resources are a valuable tool for researchers to study the molecular and genetic characteristics of tumours.

Supporting and promoting access to biological resources and the implementation of perfectly annotated BCBs is at the heart of SIRIC Montpellier Cancer’s strategy, which aims to increase cancer research capacities and make a significant contribution to the development of personalized medicine.

Colon-LR Collection

Under the research program dedicated to colorectal cancer, the Montpellier SIRIC coordinates a regional network for the collection of pre-neoplastic and neoplastic colonic tissue. The constitution of the Colon-LR clinico-biological base aims to facilitate access to colonic tissue samples associated with clinical, biological and epidemiological data for the scientific and medical community. The target is to accelerate the development of preclinical and translational projects that will ultimately lead to a better understanding of colonic tumorigenesis and metastasis dissemination mechanisms.

A first tumor microarray (TMA) was constituted from 46 patients with pre-neoplastic lesions and different stages of the disease.

How to get samples?

The BCB Colon-LR data and biological material transfer occurs after validation of a research project by the Coordinating Committee of the Colorectal Cancer Program of the SIRIC and the scientific committees of the Biological Resource Centres at the ICM or the University Hospital in Montpellier.

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The ICM collections

The CRB-ICM has tissue and biological resources related to the pathologies treated at the ICM, in particular breast, colon and ovarian cancers and sarcomas.

Quality controls of biological resources are carried out throughout the treatment process:

  • histological control of tissue samples
  • quality control of DNA and RNA derivative products
  • control of storage conditions.

Patients are informed about the use of their biological resources and give their consent before samples are taken for research purposes.

How to get samples?

All requests to make biological resources available must be submitted to the decision of the Translational Research Committee (CORT) of the ICM.

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Collections of the University Hospital of Montpellier

The BRC of the University Hospital of Montpellier has biological resources in a number of areas including cells (Head: J Moreaux) and a tumor library (Head: V Rigau). Some themes are certified according to the NFS 96-900 standard. The catalogue of biological resources offered by the BRC of the CHU of Montpellier is available on the CHU of Montpellier website.

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